Impaired lymphocyte function in depressive illness

Impaired lymphocyte function in depressive illness.

Mood states and immunity may be related. To investigate the immune status of patients with primary depressive illness, we compared in-vitro lymphocytic responses to three different mitogens in 26 drug-free depressed patients and 20 normal controls of comparable age and sex. We observed a generalized and marked decrease in the lymphocyte mitogenic activity among the depressive group. This defect...

Depressive Illness in India1

"Melancholia is one of the great words of Psychiatry. Suffering many mutations, at one time the guardian of outworn schemes of errant theories, presently misused, cavilled at, dispossessed, it has endured into our own times, as part of medical terminology no less than of common sense" (Lewis,, 1931). A disease of antiquity, depression is £.n illness with a long ancestry. As in other instances, ...

Urine concentration in depressive illness.

A total of 132 urine specimens were obtained from 17 depressed patients and 18 controls under conditions of mild water deprivation. Mean values of milliosmoles of solute and millilitres of urine excreted per hour were obtained for each subject. The depressed patients excreted significantly less solute than the control group per unit volume of urine. There was no significant difference between t...

[Impaired B lymphocyte function during open heart surgery].

Sequential in vitro lymphocyte function tests in 13 patients undergoing cardiac operation were performed to study B lymphocyte function following operation. Lymphocytes were stimulated with phytohemagglutinin (PHA), pokeweed mitogen (PWM) and Staphylococcus aureus Cowan 1 (SAC). Mitogen responses were measured by 3H-labeled thymidine incorporation. The SAC responses were significantly depressed...

Electrolytes and depressive illness.